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Multivariable logistic regression analysis was performed to identify predictive value of the APPLE, CHADS 2, CHA 2DS 2-VASc scores for arrhythmia recurrences. The differences between continuous values were assessed using an unpaired two-tailed t-test for normally distributed continuous variables, a Mann–Whitney test for skewed variables, and a chi-square test for nominal variables. Data are presented as means and standard deviation for normally distributed continuous variables and as proportions for categorical variables.

The APPLE score comprised maximum 5 points (one point for Age >65 years, Persistent AF, im Paired eGFR [30 seconds between 3 and 12 months after ablation.Īll statistical analyses were performed with SPSS statistical software version 22 (SPSS Inc., Chicago, USA). All methods were performed in accordance with the relevant guidelines and regulations. Patients provided written informed consent. Institutional Review Board of Heart Center Leipzig approved the analysis.

The study was performed according to the Declaration of Helsinki and Institutional Guidelines. The study population consisted of patients from The Heart Center Leipzig AF Ablation Registry, Germany undergoing repeat (≥2) ablation according to current guidelines between January 2007 and December 2011. However, whether the APPLE score is useful in prediction of rhythm outcomes in patients following repeat catheter ablation is unknown and was analyzed in this study. APPLE score, and demonstrated good prediction of arrhythmia recurrences before first ablation. īased on the results of a previous study, we developed and validated a new scoring system for arrhythmia recurrences, i.e. Some recent studies analyzed predictive value of widely used CHA 2DS 2-VASc score for prediction of arrhythmia recurrences after repeat catheter ablation and demonstrated inconsistent results.

ALARMEc and BASE-AF 2 –for the prediction of rhythm outcomes following catheter ablation. This led to the development of different, partly complicated, scores–e.g. Several observational studies have investigated predictors of arrhythmia recurrence in first procedures. Although medical therapy has limited efficacy compared to invasive AF treatment, arrhythmia recurrences occur in up to 50% of patients within one year after first catheter ablation, while after repeat ablation they still occur in up to 20%. Atrial fibrillation (AF) is the most common clinical arrhythmia associated with significant complications and impaired quality of life.

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